Chromosomal Abnormalities in Embryos | Dr Kaushiki Dwivedee
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Chromosomal Abnormalities in Embryos:
Chromosomal Abnormalities in Embryos stimulated during IVF is encounters more commonly .
The possible reason for the stimulation of eggs which were abnormal and meant to have atresia and not grow further. We tend to stimulate them with a high level of FSH than normal and thus a lot of embryos which grow in culture are chromosomally abnormal. That’s the reason the IVF success rate is 35 % and not 100%.
Also chromosomal abnormalities like Down’s syndrome increase with increasing maternal age. With the passage of time, the egg quality isn’t as good.
Most of the women undergoing IVF in the higher age group and thus increased chance of aneuploidy.
There are ways to detect chromosomally abnormal cells Preconception by PGT-A as well post conception by getting tested for it by NIPT which tests placental DNA.