Chromosomal Abnormalities | Dr Kaushiki Dwivedee

Chromosomal Abnormalities in Embryos stimulated during IVF is encounters more commonly .

The possible reason of stimulation of eggs which were abnormal and meant to have atresia and not grow further . We tend to stimulate them with high level of FSH than normal and thus a lot of embryos which grow in culture are chromosomally abnormal . That’s the reason the IVF success rate is 35 % and not 100%.
Also chromosomal abnormalities like Down’s syndrome increase with increasing maternal age . With passage of time the egg quality isn’t as good .
Most of the women undergoing IVF in the higher age group and thus increased chance of aneuploidy .
There are ways to detect chromosomally abnormal cells Pre conception by PGT-A as well post conception by getting tested for it by NIPT which tests placental DNA.